The Potential Threat of Vacuum Decay, The Most Efficient Way to Destroy the Universe

Kurzgesagt explained the potential threat of vacuum decay, the most efficient way to destroy the universe. Although it is only theoretical at this point, vacuum decay could not only end the universe as we know it, but rewrite the rules of physics and chemistry at the same time.

What if there is a way to destroy the universe so fundamentally that life as we know it will be impossible forever?