This 1983 public service announcement from the Long Island Regional Poison Control Center stars high-pitched talking and singing blue puppet pills who warn of the serious effects of unbottled prescription drugs that look like candy. Incidentally, rapper Busta Rhymes uses lyrics from this PSA in his 1997 song, Dangerous.
This is serious (serious),
We could make you delirious (delirious),
You should have a healthy fear of us (fear of us).