After The Brady Bunch ended in 1974, actor Robert Reed (Mike Brady) showed off his acting chops and played a doctor who wants to go through a sex change operation in a touching episode of the TV series Medical Center. There is both pre-op and post-op footage of the episode available on YouTube from Conelrad. The two-part episode aired in 1975 and was called the The Fourth Sex. It was clearly ahead of its time and earned Reed an Emmy nomination.
via Dangerous Minds